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Serum neurofilament light chain (NfL)and CSF glial fibrillary acidic protein (GFAP) together improve the prediction of long-term clinical outcomes in multiple sclerosis

Serum Glial Fibrillary Acidic Protein compared with Neurofilament Light Chain as Biomarker for Multiple Sclerosis Disease Progression

Author:Meier, Stephanie   Benkert, Pascal   Maleska Maceski, Aleksandra   Schaedelin, Sabine   Oechtering, Johanna   Melie-Garcia, Lester   Cagol, Alessandro   Barakovic, Muhamed   Galbusera, Riccardo   Achtnichts, Lutz   Lalive, Patrice H.   Bridel, Claire   Müller, Stefanie   Pot, Caroline   Salmen, Anke   Disanto, Giulio   Zecca, Chiara   Abdelhak, Ahmed   Barro, Christian   Thebault, Simon   D’Souza, Marcus   Derfuss, Tobias   Orleth, Annette   Khalil, Michael   Yaldizli, Özguer   Hermesdorf, Marco   Wiendl, Heinz   Piehl, Fredrik   Fischer, Urs   Kappos, Ludwig   Gobbi, Claudio   Granziera, Cristina   Leppert, David   Willemse, Eline A.J.   Kuhle, Jens   

Session Name:P5: MS Prognosis/Epidemiology  

Topic:MS and Inflammatory Disease  

Program Number:P5.016  

Author Institution:Multiple Sclerosis Centre and Research Center for Clinical Neuroimmunology and Neuroscience (RC2NB), Departments of Biomedicine and Clinical Research, University Hospital and University of Basel, Basel, Switzerland, Basel, Switzerland  Translational Imaging in Neurology (ThINK) Basel, Department of Biomedical Engineering  Multiple Sclerosis Centre and Research Center for Clinical Neuroimmunology and Neuroscience (RC2NB), Departments of Biomedicine and Clinical Research, University Hospital and University of Basel, Basel, Switzerland, Allschwill, Basel, Switzerland  Department of Neurology, Cantonal Hospital Aarau, Aarau, Switzerland, Aarau, Switzerland  Department of Clinical Neurosciences, Division of Neurology, Unit of Neuroimmunology, University Hospital of Geneva and Faculty of Medicine, Geneva, Switzerland, Geneva, Switzerland  Department of Neurology, Cantonal Hospital St. Gallen, St. Gallen, Switzerland, St. Gallen, Switzerland  Service of Neurology, Department of Clinical Neurosciences, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland, Lausanne, Switzerland  Department of Neurology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland, Bern, Switzerland  Multiple Sclerosis Center (MSC), Department of Neurology, Neurocenter of Southern Switzerland  Faculty of Biomedical Sciences, Università della Svizzera Italiana (USI), Lugano, Switzerland, Lugano, Switzerland  Weill Institute for Neurosciences, Department of Neurology, University of California at San Francisco (UCSF), San Francisco, California, USA, San Francisco, CA  Department of Neurology, Harvard Medical School, Boston, MA, USA, Boston, MA  Department of Medicine and the Ottawa Hospital Research Institute, University of Ottawa, Ottawa, Canada, Ottowa, ON, Canada  Department of Neurology, Medical University of Graz, Graz, Austria, Graz, Austria  Institute of Epidemiology and Social Medicine, University of Münster, Münster, Germany, Münster, Germany  Department of Neurology with Institute of Translational Neurology, University Hospital Münster, Münster, Germany, Muenster, Germany  Department of Clinical Neuroscience, Karolinska Institutet, Center for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden  Center for Neurology, Academic Specialist Center, Stockholm Health Services, Stockholm, Sweden, Stockholm, Sweden